Molecular devices introduces the flipr penta system. Options incorporating filters will block aerosol contaminants to protect both the equipment and. Flipr assay kits employ a quenching dye to reduce background fluorescence and improve the signaltonoise ratio. Molecular devices data analysis package, softmax pro 4. Apr 23, 20 sunnyvale, california, april 23 20 molecular devices announced today the launch of flipr calcium 6 assay kits, the latest addition to their extensive range of calcium assay kits to address diversified gpcr and ion channel targets. The molecular devices flipr tetra is a high throughput cellular screening platform offering superior performance and consistency in conducting real time kinetic cellular assays. The patented quench technology is offered to drug discovery and life science researchers exclusively by molecular devices, through the purchase of flipr assay kits. Molecular devices emax plus microplate reader for sale labx. Flipr membrane potential assay kit molecular devices. Recently, molecular devices released clampfit 11 software with advanced event detection functions to automate data analysis and improve accurate measurement. Molecular devices flipr tetra plus fliprtetra plus ebay. A molecular devices aquamax dw4 was used to dispense cells into 1536well microplates. How a complete set of software and validation tools for. The sterile or nonsterile pipet tips draw and dispense specific volumes by releasing the partial vacuum.
It comes with a dell desktop computer loaded with softmax pro version 4. Biocompare is the leading resource for uptodate product information, product. Danaher is a holding company and doesnt care about its small opcos like molecular devices, and it shows. Partner with molecular devices and transform your cancer research into unique biological insights. This instrument is designed to run both read and pipetting functions concurrently, making it the ideal system for rapid kinetic cellular assays, including those for. Support options incredible breadth of services that include fixedprice service plans, time and materials, qualification and validation, preventative maintenance, and relocation. Flipr penta highthroughput cellular screening system. It can be enhanced with tip washing, by integration with various plate handling systems, and through use of screenworks peakpro analysis software. Backed by the molecular devices warranty, these tips are manufactured specifically to work with the flipr instrument under strict controls to guarantee optimal performance and quality.
Molecular devices corporation developed the flipr membrane potential assay kit to provide a fast, simple and reliable fluorescence assay for detecting changes in membrane potential. Molecular devices launches nowash potassium ion channel. Laboratories operating under gmp or glp regulations must follow guidelines set by agencies to protect scientific integrity or demonstrate quality assurance of manufactured products. The flipr membrane potential assay kits deliver homogenous fluorescencebased formulations for observation of realtime membrane potential changes associated with ion channel activation and ion transporter proteins each homogeneous assay kit utilizes a proprietary indicator dye and quencher combination to maximize cell linechannelcompound applicability, while eliminating causes of data.
The molecular devices flipr is designed for screening to address kinetic based assays with liquid transfers, and multiwavelength kenetic reading for optimal general laboratory use. They will also learn the role of calcium kinetics in cardiac safety testing. Ensure your assay quality with quality tips certified rnasednasefree nonpyrogenic nonsterile. Molecular devices competitors, revenue and employees owler.
Measuring membrane potential using the flipr membrane potential assay kit on fluorometric imaging plate reader flipr systems. R8190 flipr calcium 6 explorer kit flipr calcium 6. Molecular devices flipr tips molecular devices online store. Flipr calcium assay kits from molecular devices employ sensitive calcium indicators and proprietary masking dyes to enable researchers to conduct highly sensitive fluorescent screens of gprotein coupled receptors gpcrs, ion channels, and other calcium sensitive targets.
Carole crittenden, applications scientist i molecular devices. The patented quench technology is offered to drug discovery and life science researchers exclusively by molecular devices, through the purchase of flipr assay. Screenworks peak pro software from molecular devices llc. Innovations tv tours our corporate offices and laboratories in san jose, california to demonstrate how new technologies enable great insights. Each homogeneous assay kit utilizes a proprietary indicator dye and quencher combination to maximize ce. Flipr membrane potential assay kits molecular devices. Not the cheapest kit, but instrument of choice for this application. Molecular devices is a provider of bioanalytical measurement systems, software and consumables for life science research organizations. Softmax pro allows you to create files containing all of the parameters required for acquiring and analyzing data from molecular devices microplate system instruments.
Molecular devices features cardiomyocyte screening with the flipr system and more in educational webinar with pivot park screening centre ppsc share article in this webinar, which labroots will host october 23, attendees will learn about cardiomyocyte screening, how to use full automation to perform complex gpcr testing, and more about how. Molecular devices your scientific network labroots. Here, you will see an overview of new event detection features in clampfit 11 software as well as a demonstration of template search, population spike search and action potential search. R8190 flipr calcium 6 explorer kit flipr calcium 6 assay kits, molecular devices each.
Prweb october 02, 2018 through this webinar, sponsored by molecular devices, participants will learn tips and best practices for 1536well flipr screening. To observe changes in intracellular calcium levels, cells must be loaded with a calcium sensitive fluorescent dye. Molecular devices flipr tetra system for sale labx. Flipr 1536well application in high throughput screening. Featuring a proprietary fluorophore, the dye offers the highest quantum yield of any calcium indicator on the market, delivering the greatest signal window available in a calcium assay kit. Molecular devices, llc, a leader in protein and cell biology technologies, today announced the launch of the next generation of its flipr penta highthroughput cellular screening system. Director of product marketing at molecular devices. Intracellular calcium measurements, flipr calcium assay kit. R8190 flipr calcium 6 explorer kit flipr calcium 6 assay. This is a preownedmolecular devices vmax kinetic microplate reader. On april 30, 2020, sartorius ag acquired life science company fortebio, the former biologics business unit of molecular devices.
Flipr tetra high throughput cellular screening system from. The system provides a reliable and flexible highthroughput screening solution for identifying early leads in the drug discovery process. Molecular devices, llc, a leader in protein and cell biology technologies, today announced the launch of the next generation of its flipr penta highthroughput cellular screening system the new flipr penta system builds on the success of the industryleading flipr platform for monitoring of gpcrs and ion channels, offering a new highspeed camera option capable of capturing key. Molecular devices is one of the leading provider of highperformance bioanalytical measurement solutions for life science research, pharmaceutical and biotherapeutic development. A refreshingly straight forward for a moldev device. Molecular devices features cardiomyocyte screening. Flipr tetra highthroughput cellular screening system. Characterize compound effects in human ipscderived.
Company molecular devices llc this product is no longer available on biocompare. Molecular devices introduces screenworks peak pro software. For more information about flipr tetra, flipr reagent kits, and flipr accessories, contact your molecular devices representative or visit our web site at. As one of the worlds leading providers of innovative analytical instruments, software and reagents for life science research, pharmaceutical and biotherapeutic development, we are empowering scientists to. Flipr tetra high throughput cellular screening from.
Purchase and get quotes on the products you need for your lab. An industryrenowned instrument for monitoring gpcrs and ion channels. By using a novel dye formulation to further enhance the calcium flux assay signal window, assay robustness. Flipr tetra highthroughput cellular screening molecular devices. See the new features of the flipr penta system and screenworks peak pro 2 software. Molecular devices announced today the launch of flipr calcium 6 assay kits, the latest addition to their extensive range of calcium assay kits to address diversified gpcr and ion channel targets. Intracellular calcium measurements, flipr calcium assay. Required equipment, consumables, and software the following equipment, consumables, and software are required in addition to the materials specified in the icell cardiomyocytes users guide. The simple and reliable mixandread assay format of molecular devices flipr calcium assay kit. The molecular devices flipr penta with the peak pro 2 software, tailored especially for kinetic screening for toxicology and lead compound identification, is a customizable, allinone highthroughput cellular screening system. Molecular devices is one stop destination for easy to use variety of assay kits like gpcr, ion channel, ion channel, spectramax quant dsdna, spectramax etc.
Parallel performance comparison of fluo3 and fluo4 on molecular devices flipr systemtable 19. The item was removed from a biotech in working condition, and sold because that site was being decommissioned. Jan 16, 2020 the molecular devices flipr penta with the peak pro 2 software, tailored especially for kinetic screening for toxicology and lead compound identification, is a customizable, allinone highthroughput cellular screening system. Item vendor catalog number equipment flipr tetra high throughput cellular screening system flipr tetra system molecular devices consumables. With simultaneous pipette and read function, the system supports fast kinetic cellular assays. This instrument is designed to run both read and pipetting functions concurrently, making it the ideal system for rapid kinetic cellular assays, including those for calcium flux, gpcr and ion channel read more. Screenworks peak pro software for the flipr tetra cellular screening systems enables you to visualize and analyze temporal response curves associated. Flipr fluorescent imaging plate reader was developed to perform quantitative optical screening for cellbased kinetic assays. Molecular devices corporation, 11 orleans drive, sunnyvale, ca 94089. The flipr membrane potential assay kits deliver homogenous fluorescencebased formulations for observation of realtime membrane potential changes associated with ion channel activation and ion transporter proteins. Each kit uses a proprietary indicator dye, combined with different quencher to maximize cell linechannelcompound applicability while eliminating causes of variability in the data. These kits are used for life science research, drug discovery, development and bioassays. Powered by a new, optional highspeed emccd camera and the new peak pro 2 software module, the new flipr penta highthroughput cellular screening system allows you to measure and analyze peaks of humanderived induced pluripotent stem cells hipscs, differentiated into cardiomyocytes and neurons, up to 100 times per. Molecular devices introduces the flipr penta system molecular.
May 24, 2012 molecular devices, llc, has introduced the screenworks peak pro analysis module for the flipr tetra system. The software offers the ability to analyze multipeak calcium oscillation responses of cells, and in particular beating cardiomyocytes, to characterize cardiotoxic and cardioactive compounds. Our imaging cytometry platform offers visual confidence and cellbycell statistics that would be intuitive for researches already familiar with a microplate reader workflow. Broadest selection of calcium kits to address diversified gpcr and ion channel targets flipr calcium 6 assay kits boost calcium signals, allowing you to screen poor responders while tailoring conditions to your targets specific needs. Molecular devices introduces flipr calcium 6 assay kits. Molecular devices then acquired universal imaging corporation in 2002, axon instruments in 2004, and blueshift technologies in 2008, broadening its portfolio to include electrophysiology products, scanners and analysis software for microarrays, and workstations for cellbased screening using highresolution imaging. The flipr 384 system fluorometric imaging plate reader. The trademarks used herein are the property of molecular devices, llc. Introducing screenworks peak pro software for flipr. Flipr membrane potential assay kit molecular devices online. Manufactured with different resistance levels, the devices can accommodate even corrosive or viscous materials. Molecular devices introduces the flipr penta system ibo. Molecular devices flipr american laboratory trading.
The molecular devices flipr is designed for screening to address kinetic based assays with liquid transfers, and multiwavelength kenetic reading for optimal general laboratory use specifications. Purchasing a flipr system from molecular devices assures users that they are investing in a technology that can grow with them. Molecular devices competitors, revenue and employees. Molecular devices flipr tetra system the fliprtetra system steps forward to deliver an entirely new screening platform to address realtime kinetic cellbased assays. In seconds, set up the reader with predefined protocols and run your samples with the emax plus microplate reader. Molecular devices is one of the worlds leading providers of highperformance bioanalytical measurement systems, software and consumables for life science. Jul 31, 2019 the expanded capabilities of the flipr penta system will allow scientists studying stem cellderived neuronal and cardiac cells to better characterize physiologic effects of compounds, explains sarah vargashurlston, sr. The new flipr penta system builds on the success of the industryleading flipr platform for monitoring of gpcrs and ion channels, offering a new highspeed. Learn how to evaluate compound induced effects on hipscderived cardiomyocytes.
The flipr 384 system comes complete with 384 simultaneous fluid additions, and enhanced automation features which allow linear robotics integration. Introduction softmax pro software controls molecular devices spectrophotometers, absorbance, luminescence, and fluorescence microplate re adersproviding extensive data calculation and analysis capabilities under a glpgmp work environment for pharmaceutical, bio. Parallel performance comparison of fluo3 and fluo4 on. Molecular devices headquarters is located in san jose, california, usa 95. Molecular devices emax plus microplate reader running elisas and protein quantification is simpler than ever with the emax plus microplate reader. The software offers the ability to analyze multipeak calcium oscillation responses of cells, and in particular beating cardiomyocytes, to characterize cardiotoxic and cardioactive compounds during a high throughput screen. New flipr penta cellular screening system from molecular. Introducing screenworks peak pro software for flipr tetra. You may also import data from other molecular devices instruments such as analyst and flipr systems for display and analysis. How a complete set of software and validation tools for microplate readers can help gmpglp labs meet fda data integrity guidelines. Feb 14, 2012 sunnyvale, ca february 14, 2012 molecular devices, llc, introduces the screenworks peak pro analysis module for the flipr tetra system.
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